Evodia
lepta三叉苦 Sān chā kǔ
Evodia Family: Rutaceae PART USED: Dried branch and leaf FLAVOR: Bitter FUNCTIONS
1. Clear Heat and counteract toxic effects.[1,2]
2. Heal inflammation, relieve pain.[2]
3. Alleviates itching.[1] INDICATIONS
1. Common Cold, fever, tonsillitis, laryngitis.[2]
Epidemic influenza, sore throat.[1]
2. Epidemic encephalomyelitis, encephalitis B.[2]
Meningitis, infectious hepatitis.[1]
2. Rheumatoid arthritis pain.[1,2]
Traumatic injuries.[1]
3. Chicken pox, hemorrhoids.[1]
4. External use for swelling and itch.[2] PATENT COMBINATIONS
- Flu and colds at the first stage: Exterior releasing- cooling-
The diaphoretic action (sweating effect) moves circulation to the surface to clear
invading microbes affecting the Lungs/throat- Gan
mao ling.
PREPARATIONS:Decoction.
Dried branch and leaf 9-15 g.[2]
Roots and leaves 9-15 g.[1] HABITAT:
Along forest edges, on hillsides and along streams. DESCRIPTION: Shrub or small deciduous tree. Grows to a height of 2-5 m,
bark greyish-white. Leaves; opposite, palmate trifoliate, with long petioles,
elliptical-lanceolate, apexes acute, bases narrow, margins intact. Flowers; occur
during spring and summer, numerous auxillary yellowish-white flowers appear in
a panicle inflorescence. Capsule; reddish brown. References
[1] Barefoot Doctor's Manual- 1977 Prepared by the Revolutionary Health Committee
of Hunan Province. Original Chinese manual- Victor W. Sidel. Originally published
by Dr Joseph Quin and the Fogarty International centre, Bethdesda (1974). Madrona
Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada. Images
1. Retrieved from www.wm-sec.com 19-May-14
2. [1]
Inner Path can not take any responsibility for any adverse effects from the
use of plants. Always seek advice from a professional before using a plant medicinally.
Constituents
Leaves and roots: contain
alkaloids. The leaves also contain volatile oil, the main components of which
are α-pinene and furfural.[1]
References
[1] itsfun.com.tw
Research
A new prenylated coumarin and a new anthranilamide derivative from Evodia
lepta
Xing-Lin Xie, Guo-Hua Ye, Jun-Juan Xue, Tong Su, Gui-Hua Tang, Wei Li, Sheng Yin Abstract
A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated
from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide
derivative from the Evodia genus. Their structures were elucidated by spectroscopic
data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain inhibition on
nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages
with an IC50 value of 37.96 ± 1.7 μM.
J Asian Nat Prod Res 2020 May;22(5):413-417. doi: 10.1080/10286020.2019.1670169.
Epub 2019 Sep 30. PMID: 31565970 DOI: 10.1080/10286020.2019.1670169 pubmed.ncbi.nlm.nih.gov
New furoquinoline alkaloids from the leaves of Evodia lepta
Jirapast Sichaem, Apapond Jirasirichote, Krittakorn Sapasuntikul, Suttira Khumkratok,
Pattara Sawasdee, Thi My Lien Do, Santi Tip-pyang Abstract
Three new furoquinoline alkaloids, leptanoines A-C (1-3) along with three known
compounds (4-6) were isolated from the leaves of Evodia lepta. Their structures
were identified by interpretation of their spectroscopic data as well as comparison
with those reported in the literature. In addition, all isolated compounds were
evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)
activities. Compound 4 showed the highest inhibitory activity towards BChE with
an IC50 value of 47.9 μM. On the other hand, Compound 5 showed the highest inhibitory
activity towards AChE with an IC50 value of 69.1 μM.
Fitoterapia 2014 Jan;92:270-3. doi: 10.1016/j.fitote.2013.12.002. Epub 2013 Dec
9. PMID: 24333260 DOI: 10.1016/j.fitote.2013.12.002 pubmed.ncbi.nlm.nih.gov
Characterization, Antioxidant and Antitumor Activities of Oligosaccharides
Isolated from Evodia lepta (Spreng) Merr. by Different Extraction Methods
Feng Xiong, Hui-Xian Liang, Zhi-Jing Zhang, Taifo Mahmud, Albert S C Chan, Xia
Li, Wen-Jian Lan Abstract
Evodia lepta (E. lepta) is a traditional Chinese herbal medicine with various
biological activities. One of the active components of this widely used medicinal
plant is believed to be an oligosaccharide. The extraction yields, structural
characteristics, antioxidant, and antitumor activities of four oligosaccharide
extracts obtained by hot water extraction (HEO), ultrasound-assisted extraction
(UEO), enzyme-assisted (EEO), and microwave-assisted extraction (MEO) were investigated.
Matrix-assisted laser desorption/ionization-time of flight-mass spectrometry (MALDI-TOF-MS),
X-ray diffraction (XRD), and Scanning electron microscopy (SEM) results indicated
that the extraction methods had a difference on the molecular mass distribution,
structure, and morphology of the EOs. In addition, HEO and MEO showed strong antioxidant
activities, which might be related to their uronic acid and protein contents.
More interestingly, MEO was more active toward MDA-MB-231 cells compared to other
cells, and cell growth inhibition was proposed to occur through apoptosis. Overall,
microwave-assisted extraction is a promising technique for the extraction of high
quality EO.
Antioxidants (Basel) 2021 Nov 20;10(11):1842. doi: 10.3390/antiox10111842. PMID:
34829713 PMCID: PMC8614670 DOI: 10.3390/antiox10111842 pubmed.ncbi.nlm.nih.gov
FLAVOR: Bitter
HABITAT:
Along forest edges, on hillsides and along streams.